CurcuPlex-95

delivers 500 mg of BCM-95, a patented, 100% pure turmeric extract standardized to 95% total curcuminoids complex (including curcumin, demethoxycurcumin, and bisdemethoxycurcumin at 86% curcuminoids and 65% curcumin) alongside the essential volatile oils of turmeric rhizome, in a single vegetarian capsule designed to support a healthy inflammatory response, antioxidant and cellular protection, joint health, brain and mood health, immune modulation, and healthy cell growth signaling without the use of phospholipids, excipients, additives, carriers, nanotechnology, or synthetic bioenhancers.

Curcumin is the most studied anti-inflammatory botanical compound in the world, with thousands of peer-reviewed publications documenting its activity across NF-kB, COX-2, LOX-5, and cytokine inflammatory pathways, its antioxidant activity as both a direct free radical scavenger and an Nrf2 activator, and its role in supporting healthy cell growth signaling, neurological health, mood balance, and immune system modulation. The challenge with standard curcumin extracts and even most 95% curcuminoid standardizations is bioavailability: curcumin is poorly absorbed from the gut in its pure form, metabolized and conjugated rapidly in the intestinal wall and liver, and achieves only modest plasma concentrations after standard oral dosing.

BCM-95 addresses this through an entirely different approach than most enhanced curcumin products on the market. Most enhanced bioavailability curcumin formulas use piperine (black pepper extract), phospholipid complexes, or nanoparticle technology to improve absorption. BCM-95 uses none of these. Instead, it incorporates the essential volatile oils naturally present in turmeric rhizome, the same oils that accompany curcuminoids in the whole turmeric plant, to enhance curcumin's absorption and bioavailability through a mechanism that mirrors the way curcumin is absorbed when consumed from whole turmeric root. This natural essential oil co-extraction has been shown to enhance curcumin bioavailability without introducing piperine (which can interfere with drug metabolism through CYP3A4 and P-glycoprotein pathways), without phospholipids, and without synthetic additives of any kind, making BCM-95 one of the cleanest enhanced bioavailability curcumin formulas available.

At 500 mg per capsule with the natural essential oil bioavailability enhancement, two daily capsules (1,000 mg) provides meaningful therapeutic curcumin activity across anti-inflammatory, antioxidant, neurological, and immune applications. Formulated to exclude wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, GMO-derived ingredients, artificial colors, sweeteners, and preservatives. NSF GMP-certified XYMOGEN professional formula. 120 vegetarian capsules.

Consult your healthcare practitioner before use, especially if taking blood-thinning medications or undergoing cancer treatment. Curcumin may interact with certain medications and chemotherapy agents.

Key Benefits:

• Supports a healthy inflammatory response through NF-kB, COX-2, and cytokine modulation
• Provides potent antioxidant and cellular protection via direct free radical scavenging and Nrf2 activation
• Supports joint health and helps relieve minor discomfort associated with physical activity
• Supports brain health and neuronal function
• Supports a healthy mood and emotional balance
• Supports immune health by modulating cytokine and signaling molecule production
• Supports healthy cell growth signaling in multiple cell lines
• Supports a healthy microbial environment in the gut
• BCM-95 enhanced bioavailability through natural turmeric essential oils, no piperine, no phospholipids, no synthetic additives
• 100% pure turmeric extract, no synthetic fillers or bioenhancers
• Piperine-free, safe for those on medications sensitive to CYP3A4 interactions
• Formulated to exclude gluten, dairy, soy, GMOs, and artificial ingredients
• NSF GMP-certified XYMOGEN professional formula

What's Inside — Full Supplement Facts (per 1-capsule serving):

BCM-95 Turmeric Extract (Curcuma longa, rhizome) — 500 mg Standardized to: 95% Total Curcuminoids Complex (including curcumin, curcuminoids, and volatile oils), 86% Curcuminoids, 65% Curcumin

BCM-95 is a patented, extensively studied turmeric extract produced by Dolcas-Biotech LLC, standardized to the full curcuminoid complex including all three primary curcuminoids: curcumin (the most abundant and most studied), demethoxycurcumin, and bisdemethoxycurcumin, alongside the volatile essential oils of turmeric rhizome that are naturally co-extracted with the curcuminoids in the BCM-95 process. These essential oils, primarily turmerones (ar-turmerone, alpha-turmerone, and beta-turmerone), enhance curcumin absorption by improving intestinal permeability to curcuminoids and slowing their phase II metabolism in the gut wall, resulting in significantly higher plasma curcumin concentrations compared to standard curcumin extracts at equivalent doses.

The 95% total curcuminoids standardization (86% curcuminoids, 65% curcumin) represents one of the highest curcuminoid concentrations available in a pure turmeric extract, ensuring consistent and therapeutically meaningful curcumin activity in every capsule. The multi-curcuminoid profile, delivering all three natural curcuminoids rather than isolated curcumin alone, reflects the whole-extract philosophy of BCM-95 and ensures the complementary activity of demethoxycurcumin and bisdemethoxycurcumin alongside curcumin's primary NF-kB and antioxidant mechanisms.

Other Ingredients: Capsule (hypromellose and water), dicalcium phosphate, ascorbyl palmitate, silica, and carboxymethyl cellulose. Vegetarian capsule. No piperine, no phospholipids, no synthetic bioenhancers.

Storage

Store in a cool, dry place. Keep out of reach of children.

Directions

Take 1 capsule twice daily, or as directed by your healthcare professional. Can be taken with or without food. For maximum anti-inflammatory and antioxidant activity, consistent daily use at 1,000 mg (2 capsules) per day is recommended.

Consult your healthcare professional prior to use. Individuals taking medication, especially blood thinners or those undergoing cancer treatment, should discuss potential interactions with their healthcare professional. Do not use if tamper seal is damaged.

XYMOGEN CurcuPlex-95 is a practitioner-trusted BCM-95 curcumin supplement available at SOLUDE Wellness & Beauty. It contains BCM-95 Turmeric Extract (Curcuma longa, rhizome) 500 mg per capsule, standardized to 95% total curcuminoids complex (86% curcuminoids, 65% curcumin) including curcumin, demethoxycurcumin, bisdemethoxycurcumin, and essential volatile oils of turmeric rhizome, in a vegetarian hypromellose capsule with dicalcium phosphate, ascorbyl palmitate, silica, and carboxymethyl cellulose. It is designed to support a healthy inflammatory response through NF-kB COX-2 and cytokine modulation, antioxidant and cellular protection via Nrf2 activation, joint health and minor physical activity discomfort relief, brain and neuronal health, healthy mood, immune modulation, healthy cell growth signaling, and gut microbial environment support. BCM-95 enhanced bioavailability through natural turmeric essential oils with no piperine, no phospholipids, and no synthetic additives. Piperine-free. Formulated to exclude gluten, dairy, soy, GMOs, artificial ingredients. NSF GMP-certified. 120 vegetarian capsules. Take 1 capsule twice daily.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.