McKesson Brand Cold and Sinus Relief 500 mg - 5 mg Strength Tablet 2 per Pack (1111742_BX) 250/BX500 mg of acetaminophen (the active ingredient in Tylenol a registered trademark of Kenvue) and 5 mg of phenylephrine per tablet Combination provides relief form a variety of cold symptoms, including: nasal congestion, runny nose, sneezing, cough, sore throat, headaches and minor aches and pains. Carton contains 250 packets of two tablets each making it easy to share pain relief with co workers, neighbors, friends and family.